10 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Primary Thrombotic Microangiopathy ... Differential Diagnosis Table ... • Thrombotic Thrombocytopenic ... Purpura (TTP) ... #TMA #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
of Thrombotic Thrombocytopenic ... TMA: Thrombotic microangiopathy ... HUS) Treatment ... management #treatment #rheumatology ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Consumption: - Microangiopathy ... : DIC, TTP, HUS ... Medicine @SCVMCMed #Thrombocytopenia ... Diagnosis #Framework #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... triad of MAHA + thrombocytopenia ... #Thrombotic #Microangiopathy ... #TMAs #hematology ... #hus
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
: Thrombotic thrombocytopenic ... purpura (TTP), ... uremic syndrome (HUS ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... /HUS, HELLP Syndrome ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... of child 3) TTP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
urinalysis 3) microangiopathic ... . pauci-immune GN ... PLEX (overlap TTP ... or aHUS), eculizumab ... Renal #Crisis #rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... Hepatic cirrhosis - TTP ... /HUS - Angioimmunoblastic ... mimics that of MCD; thus ... diagnosis #management #rheumatology