40 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... SLE), Sjogren's Syndrome ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... and treatment can ... • Systemic lupus ... erythematosus ... #differential #diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #Syndrome #diagnosis
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... onset of tender erythematous ... Excellent response to treatment ... with systemic corticosteroids
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Lupus Erythematosus ... Demyelinating Syndrome ... permeability Diagnosis ... #Lupus #Erythematosus
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... Inflammatory and ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Workup: - ANA ... life-threatening • Treatment ... #Summary #rheumatology