22 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... Differential Diagnosis Algorithm ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... deficiencies #Pancytopenia
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Differential #Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... HLH syndrome 5. ... Acquired Aplastic Anemia ... marrow failure syndrome ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... HLH syndrome 5 ... Acquired Aplastic Anemia ... marrow failure syndrome ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... effect following treatment ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... Differential #Diagnosis #Algorithm
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... , GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... #oncology #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... Gastrectomy, WHDA syndrome ... #Anemia #Differential ... #ferritin #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... Kawasaki, Nephrotic syndrome
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... ataxia (broad-based gait ... is Korsakoff's syndrome ... and retrograde amnesia ... diagnosis #comparison #neurology