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diagnosis differential sle symptoms systemic vasculitis ana antibodies arthritis classification patterns sjogrens syndrome aortitis autoantibodies clinical complications gout gouty imdamnsharp
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Juvenile Idiopathic Arthritis ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Discoid Rash A Antinuclear ... cytopenias) A Arthritis ... R Renal Disease ... #erythematosus ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus ( ... erythematosus ( ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology ... #signs #symptoms
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Vasculitides: Giant ... Cell Arteritis ... (RA), Systemic lupus ... erythematosus ( ... Differential #Diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
temporalis (giant-cell ... arteritis) - ... - systemic lupus ... erythematosus ... Vessels #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... #Erythematosus ... autoantibodies #signs ... #differential #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... like rheumatoid arthritis ... RA) or systemic lupus ... erythematosus ( ... Sjogrens #Syndrome #Pathophysiology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... pain (20%) Renal disease ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... erythematosus, ... purpura: strong sign ... differential #diagnosis #rheumatology
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