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Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
over-secretion of growth ... #Acromegaly #Signs ... #Symptoms #Diagnosis
Symptoms of Hypophosphatemia • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue • Hematologic:
Symptoms of Hypophosphatemia ... Osteomalacia, Growth ... Hypophosphatemia #Phosphate #Symptoms ... #Signs #Diagnosis
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... Hormone (GH) Growth ... pathway -> Incr cell growth ... activates lipolysis Signs ... /Symptoms: • GH
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... Male-pattern hair growth ... Accelerated childhood growth ... #Symptoms #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... excess prior to growth ... GH excess after growth ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
CLINICAL MANIFESTATIONS OF ADRENAL INSUFFICIENCY. Primary and secondary adrenal insufficiency: - Tiredness, weakness, mental depression
nervous system symptoms ... - Prepubertal growth ... Headache, visual symptoms ... Insufficiency #Signs ... #Symptoms #Adrenal
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... , Malnutrition Signs ... density, Impaired growth ... Deficiency #diagnosis #signs ... #riskfactors #symptoms
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Osteoblasts and Growth ... pathophysiology #signs ... #symptoms #diagnosis
Clinical Effects of Large and Small Pituitary Tumours Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Hypopituitarism • Growth ... Pituitary #Tumors #Signs ... #Symptoms #Diagnosis
Cholesteatoma (of middle ear): Pathogenesis and clinical findings • Congenital trapping of keratinizing epithelium in middle
- Destructive growth ... the middle ear Signs ... / Symptoms / Complications ... pathophysiology #symptoms ... #signs #diagnosis
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