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diagnosis management hematology lymphohistiocytosis pathophysiology symptoms treatment rheumatology criteria mas syndrome activation algorithm alopecia arteritis behcet bulimianervosa complications dermatology differential
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hemophagocytic Lymphohistiocytosis ... (HLH) Clinical ... lab findings in HLH ... consistent with HLH ... #Hemophagocytic
Proposed Treatment Algorithm for MAS / HLH #MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Algorithm for MAS / HLH ... #MAS #HLH #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... (HLH) Pathophysiology ... • Familial HLH ... Chediak-Higashi, Griscelli, Purtilo ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... (HLH) Definition ... / Diagnosis: HLH ... signs and symptoms ... #Hemophagocytic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
acquired forms of haemophagocytic ... lymphohistiocytosis (sHLH ... A subset of hemophagocytic ... lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... (HLH) Treatment ... Primary HLH: - ... HLH-94 Protocol ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009 At least three of the following: -
Hemophagocytic Lymphohistiocytosis ... (HLH) Diagnostic ... @PulmCrit #HLH ... #Hemophagocytic
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
HLA-DR4 mutation ... yrs old; F>M Signs ... Pathophysiology #Diagnosis #Signs
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
haploidentical>unrelated>HLA ... Conditioning regimen Signs ... EBV viral load, signs
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Sex Hormones (LH ... pathophysiology #signs
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