33 results
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management

- Dr. Eric Strong @DrEricStrong - Strong Medicine
- Clinical Presentation ... EricsMedicalLectures/ #VonWillebrand ... #Disease #Diagnosis ... #Management #hematology ... #treatment
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... platelet count (mild thrombocytopenia ... factor VIII) Treatment ... #Disease #Diagnosis ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
disorders • Celiac disease ... effect following treatment ... following EtOH induced thrombocytopenia ... #Algorithm #Causes ... #Hematology
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
HIT Algorithm ... • "4 T's" clinical ... #HIT #hematology ... #diagnosis #4Ts ... #algorithm
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... family history - Medications ... PT, aPTT(liver disease ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Quinidine • HIT ... #Algorithm #Causes ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Reaction to Medications ... #Algorithm #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... • HCV, HBV Not ... #hematology #rheumatology ... #nonpalpable #dermatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Causes of Isolated ... Medications ... Childhood viruses • HIV ... #Algorithm #Causes ... #Hematology