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algorithm causes management oncology pathophysiology comparison deficiency index lfts liver obstetrics polycythemia pregnancy reticulocyte thrombocytosis workup abnormal aplastic arterial aspergillus
Calculating a Reticulocyte Index (RI) Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction Absolute Reticulocyte Count =
reticulocytes x Patient's Hct ... / Normal Hct ... Index #RI #RPI #hematology ... #diagnosis #anemia
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Wilsons, Pregnancy - AFLP ... NAFLD, Others • Mild ... #hepatology #LiverFunctionTests
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... Inflammatory: • IBD ... Iron deficiency anemia ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... → Refer to hematology ... hemolysis, deficiency anemia ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Pregnancy - AFLP ... NAFLD • Others Mild ... Others #LFTs #Hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
= (Retic %) x (Hct ... Index < 2: • Anemia ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Dyspnea - Differential ... Diagnosis Framework ... • Parenchyma: ILD ... Transverse myelitis • Hematology ... : - Anemia •
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... Liver #Pregnancy #hepatology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
- Polycythemia Differential ... Diagnosis Algorithm ... Hb > 16.5 g/dL/HCT ... : Hb > 16 g/dL/HCT ... #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential ... Diagnosis Algorithm ... Tropical sprue, IBD ... #ferritin #hematology
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