16 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
VS HUS Big picture ... thrombocytopenic #purpura ... #HUS #thrombocytopenia ... Comparison #Diagnosis #Table ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... Thrombocytopenic Purpura ... (TTP) • Shiga ... HUS (aHUS) ... Microangiopathy #TMA #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
HUS), Serum creatinine ... HUS) Treatment ... #management #treatment ... #rheumatology # ... hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/HUS - Hemolytic ... /HUS • Anticoagulants ... deficiency • Liver ... Differential #Diagnosis #hematology ... #rheumatology #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombocytopenic purpura ... thrombocytopenia, Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Pregnancy - TTP ... /HUS, HELLP Syndrome ... plasma exchange 2) TTP ... AFLP #obstetrics #hematology ... #diagnosis #table
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... HBV and thus periodic ... HAV immunity; Liver ... Algorithm #Diagnosis #Management ... #Treatment #Hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... , HUS, DIC, HELLP ... Defects, Drugs, Liver ... Differential #Diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Extrinsic Causes: • Liver ... Causes: • MAHA: TTP ... , HUS, DIC, HELLP ... classification #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DDX: • TMA’s (HUS ... /HUS > DIC • Severe ... Liver Disease: ... causes #treatment #management ... #hematology