Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic antinuclear ana hematology treatment erythematosus signs disease antibodies vasculitis symptoms

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23 results

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

Associated Rheumatic Diseases ... connective tissue disease ... SLE), Sjogren's Syndrome ... #Antibodies #ANA ... #patterns #rheumatology

ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
• Systemic lupus erythematosus
1. Anti-dsDNA

ANA (Antinuclear ... connective tissue disease ... 90% • Anti-GBM disease ... #rheumatology # ... diseases

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... Disease! ... context of other symptoms ... #Antibodies #ANA ... #patterns #rheumatology

Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... c-ANCA - Vasculitis ... diagnosis #table #rheumatology

Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
• Associated

Systemic Lupus Erythematosus ... - Summary Antinuclear ... with more severe disease ... Treatment: • ... Summary #diagnosis #rheumatology

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Decade Skin Disease ... tissue disease ... diseases (i.e. ... ) • Kikuchi disease ... #Diagnosis #Rheumatology

Systemic Lupus Erythematosus - Diagnosis
Manifestations:
- Arthritis 69%
- Malar rash 40%
- Fever 36%
-

Systemic Lupus Erythematosus ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #signs #symptoms ... #differential #rheumatology

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

(Granulomatous disease ... rheumatic diseases ... atherosclerotic disease ... most important diseases ... differential #diagnosis #rheumatology

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin

Butterfly rash, Vasculitis ... pain (20%) Renal disease ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology

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