Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic disease antibodies antibody table diagnosis hematology

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23 results

Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

their Disease Associations ... (TTG) - Celiac disease ... #diagnosis #table ... #rheumatology # ... antibodies

Autoantibodies in Rheumatology
• Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and

Rheumatology • ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... #Rheumatology # ... #table

ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
• Systemic lupus erythematosus
1. Anti-dsDNA

cases • Sjögren syndrome ... connective tissue disease ... 90% • Anti-GBM disease ... #diagnosis #rheumatology ... #diseases

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

or Anti-NucIear Antibody ... ANA ≠ Autoimmune Disease ... • Rheumatic Diseases ... ANA #patterns #rheumatology ... #diagnosis #differential

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

Associated Rheumatic Diseases ... connective tissue disease ... SLE), Sjogren's Syndrome ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology

Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.

Connective tissue disease-associated ... interstitial lung diseases ... PSS: Sjogren syndrome ... connective tissue disease ... #Pulmonary #Rheumatology

Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory

Congenital Diseases ... Wiskott-Aldrich syndrome ... and Autoimmune Diseases ... : • Systemic lupus ... #Hematology

Systemic Lupus Erythematosus - Diagnosis
Manifestations:
- Arthritis 69%
- Malar rash 40%
- Fever 36%
-

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... #rheumatology # ... table #ANA

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

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