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differential management lupus erythematosus sle algorithm antinuclear causes dermatology oncology table treatment vasculitis classification pancytopenia signs symptoms anemia associations chronic
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic Diseases ... connective tissue disease ... #ANA #patterns ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Disease! ... : The ANA patterns ... Rheumatic Diseases ... #ANA #patterns ... #rheumatology #diagnosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... #rheumatology # ... antibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... #Rheumatology # ... diagnosis #associations
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
cases • Sjögren syndrome ... connective tissue disease ... 90% • Anti-GBM disease ... #diagnosis #rheumatology ... #diseases
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... Associated Autoantibodies ... : Diffuse skin disease ... : Limited skin disease ... #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
- Kawasaki disease ... infectious diseases ... - serum disease ... #Rheumatology # ... Diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
: - ANA 95-100% ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #autoantibodies ... #differential #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
with more severe disease ... Used to monitor disease ... with more severe disease ... #SLE #Summary #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... tissue disease ... diseases (i.e. ... ) • Kikuchi disease ... #Rheumatology
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