17 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... #rheumatology # ... antibodies
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • ... Lupus (SLE): ANA ... others (RNP, aPL antibodies ... #Rheumatology # ... #associations #table
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANAAutoimmune ... Disease! ... Rheumatic Diseases ... • Rheumatic Diseases ... #rheumatology #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
cases • Sjögren syndrome ... connective tissue disease ... 90% • Anti-GBM disease ... #diagnosis #rheumatology ... #diseases
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Management • ... Autoantibodies to ... thrombocythemia), Autoimmune ... disease • vWF ... #treatment #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... tissue disease ... rheumatologic diseases ... ) • Kikuchi disease ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... demyelinating disease ... Tracheobronchial disease ... #Rheumatology #
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
and Systemic lupus ... Association with disease ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... the formation of autoantibodies ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... female, asian • Systemic ... IgG4 #Related #Disease ... #phenotypes #workup ... #treatment #rheumatology