Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic disease diagnosis antibodies lupus ana table summary antinuclear autoimmune druginduced

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15 results

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... Positive ANA ≠ Autoimmune ... : Lupus (SLE), Systemic ... #Antibodies #ANA ... #patterns #rheumatology

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

Associated Rheumatic Diseases ... connective tissue disease ... SLE), Sjogren's Syndrome ... #Antibodies #ANA ... #patterns #rheumatology

Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... #diagnosis #table ... antibodies

Autoantibodies in Rheumatology
• Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and

Lupus (SLE): ANA ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... diagnosis #associations ... #table

ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
• Systemic lupus erythematosus
1. Anti-dsDNA

) • Systemic lupus ... connective tissue disease ... 90% • Anti-GBM disease ... #antibodies #diagnosis ... diseases

Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
• Associated

Systemic Lupus Erythematosus ... - Summary Antinuclear ... (ANA) - 95% - Initial ... with more severe disease ... diagnosis #rheumatology

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Antinuclear antibodies ... and Systemic lupus ... Association with disease ... with auto-immune diseases ... table #ANA

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... Decade Skin Disease ... tissue disease ... rheumatologic diseases ... #Diagnosis #Rheumatology

Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
• Epidemiology: -10% of all lupus cases, drug-dependent,

of autoantibodies ... months to years) Systemic ... Evolution: Chronic disease ... #table #rheumatology ... #diagnosis #management

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

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