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ana antibodies differential table erythematosus lupus anca antineutrophil arthritis chronic classification conditions cryoglobulinemia cryoglobulins extrarticular joint laboratory leukemia lymphocytic pain
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... connective tissue disease ... (TTG) - Celiac disease ... diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • ... Lupus (SLE): ANA ... • Scleroderma (Systemic ... #Rheumatology # ... diagnosis #associations
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... connective tissue disease ... 90% • Anti-GBM disease ... #rheumatology # ... diseases
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... overlap syndromes ... with auto-immune diseases ... #autoantibodies ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... Antiphospholipid-antibody ... , Lyme disease, ... #differential #diagnosis ... #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... connective-tissue disease ... #Disease #Rheumatoid ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Autoimmune diseases ... : - 10% SLE or ... Antineutrophil cytoplasmic antibody ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... diseases (i.e. ... ) • Kikuchi disease ... #Rheumatology
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