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differential lupus management table classification erythematosus sle associations hematology patterns signs symptoms anca antibody antineutrophil aortitis autoimmune behcet chronic cll
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... #Antibodies #ANA
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... c-ANCA - Vasculitis ... antibodies
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
- Kawasaki disease ... infectious diseases ... - serum disease ... #Rheumatology # ... Diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... connective tissue disease ... 90% • Anti-GBM disease ... #antibodies #diagnosis ... diseases
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Disease! ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... Ill • ANCA Vasculitis ... diagnosis #associations
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
, Cogan's Syndrome ... polychondritis, Behcet's Disease ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... (RA), Systemic
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... • Whipple's disease ... , Vasculitis (e.g ... #differential #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... diseases, such ... atherosclerotic disease ... most important diseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Still disease, ... tissue disease ... diseases (i.e. ... ) • Kikuchi disease
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