Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic disease diagnosis classification antibodies hematology differential antinuclear management

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19 results

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

Associated Rheumatic Diseases ... connective tissue disease ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential

Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

their Disease Associations ... (TTG) - Celiac disease ... #Associations #diseases ... #rheumatology # ... antibodies

ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
• Systemic lupus erythematosus
1. Anti-dsDNA

cases • Sjögren syndrome ... connective tissue disease ... 90% • Anti-GBM disease ... #diagnosis #rheumatology ... #diseases

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... ANA ≠ Autoimmune Disease ... • Rheumatic Diseases ... #patterns #rheumatology ... #diagnosis #differential

Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
• Associated

- Summary Antinuclear ... with more severe disease ... #SLE #Summary #diagnosis ... #rheumatology # ... management

Systemic Lupus Erythematosus - Diagnosis
Manifestations:
- Arthritis 69%
- Malar rash 40%
- Fever 36%
-

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... #autoantibodies ... #rheumatology #

Acquired von Willebrand Syndrome - Diagnosis and Management
• Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,

Autoantibodies to ... thrombocythemia), Autoimmune disease ... #Diagnosis #Management ... #treatment #hematology ... #differential

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Decade Skin Disease ... Classification: ... diseases (i.e. ... ) • Kikuchi disease ... #Rheumatology

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