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diagnosis differential management hematology acr2021 associations autoantibodies diseases granulomatosis guidelines polyangiitis table ana antibody antineutrophil antinuclear arterial causes classification dermatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... cases • Sjögren syndrome ... Vasculitis: • ... Renal-limited vasculitis ... #diagnosis #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... Vasculitis: P-ANCA
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Causes #Hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Vasculitis, e.g ... granulomatosis p-ANCA ... - Vasculitis, e.g ... diagnosis #table #rheumatology ... #antibodies
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis: + MPO-ANCA ... : • Behçet Syndrome ... • Cogan Syndrome ... ) pattern: antibodies ... differential #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Purpura Anti-GBM antibodies ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Proposed treatment algorithm for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis #anca #vasculitis #treatment #algorithm #rheumatology #nephrology
Proposed treatment ... )-associated vasculitis ... #anca #vasculitis ... #treatment #algorithm ... #rheumatology #
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Treatment #ACR2021 ... #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... #Treatment #ACR2021 ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Cryoglobulinemia (MIXED) • ANCA ... #rheumatology #
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