13 results
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Differential Diagnosis Table ... #Anemia #AIHA # ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... - Autoimmune (AIHA ... ) (e.g. lupus, CLL ... differential #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
• Cold AIHA ... • Drug-induced AIHA ... • Sickle cell ... anemia • ... Algorithm #Causes #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
formerly known as atypical ... organ or stem cell ... anemia" • HELLP ... differential #diagnosis #hematology ... #hemolysis
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... cells: Sickle cell ... Alcohol abuse, Heavy ... Smear #Analysis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA ... Defects: Sickle cell ... anemia, Thalassemias ... Differential #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
women • 15% of AIHA ... • Symptoms of anemia ... anemia • Cold ... malignancies -> CLL ... #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes with typical ... 5) Symptoms of anemia ... cytopenias (ITP, AIHA ... →several RCTs have ... Leukemia #oncology #hematology
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
therapy is non-pharmacologic ... the first line pharmacologic ... If all topical products ... #Medications #Pharmacology ... #Dermatology #Management
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
After non-pharmacologic ... Remember that all ... You may have seen ... #Medications #Pharmacology ... #Dermatology #Management