13 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... ) Blood (75%): Anemia ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... #Lupus #Erythematosus ... #signs #symptoms ... #differential #rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... Can progress to MDS ... #diagnosis #management ... #treatment #hematology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
and Arthritis in Pediatrics ... - Differential Diagnosis ... In POC redness may ... migrans: • Target sign ... Suggestive of systemic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... (NPSLE): • May ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
when infection has ... including in children (pediatric ... #sle #clues #system ... #erythematosus ... #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... complaints- anemia ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... present, symptoms, signs ... • Treatment algorithms ... #Management #Summary ... #treatment #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
may take 6 to 8 ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management