25 results
Hemimasticatory Spasm (HMS) on Physical Exam

HMS is characterized by paroxysmal involuntary contractions of the unilateral jaw-closing
Hemimasticatory ... trigeminal nerve #Hemimasticatory ... neurology #trigeminal #CN5 ... #CNV
Common toxicities of antifungal agents. 
CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
CNS = central nervous ... antifungal #toxicities #SideEffects ... #Adverse #Pharmacology
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
Antibiotics and CNS ... Drugs with good CNS ... with moderate CNS ... Drugs with low CNS ... Perfusion #CSF #Pharmacology
IDSA Aspergillosis Treatment
 • Invasive pulmonary aspergillosis (IPA)
 • CNS aspergillosis
 • Cardiac Aspergillus infection
 •
aspergillosis (IPA) • CNS ... Treatment #management #pharmacology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
nervous system (CNS ... effects on the CNS ... receptor subunits at CNS ... effects on the CNS ... nuclei in the CNS
Hemimasticatory Spasm on Physical Exam

Hemimasticatory spasm is a disorder of the trigeminal nerve → involuntary jaw
Hemimasticatory ... Physical Exam Hemimasticatory ... @bobvarkey #Hemimasticatory ... clinical #cheek #CN5
Effects of H1 Antihistamines at Histamine, Adrenergic, Cholinergic, and Serotonin-Binding Receptors
Cholinergic - Incr Dry mouth, Incr
Neurotransmission in the CNS ... Antihistamines #Pharmacology
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
- Symptoms of CNS ... CNS depression will ... Diagnosis #Management #Pharmacology
Central Nervous System Pharmacology - Somatic and Autonomic Receptors
Somatic
 • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
Nervous System Pharmacology ... NervousSystem #CNS ... Autonomic #Receptors #Pharmacology
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
co-ingestion with other CNS ... Benzodiazepines #Psychiatry #Pharmacology