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diagnosis hematology causes algorithm hemolysis extravascular intravascular pulmonary agglutinin anemias disease fever infections intermittent lung management patterns periodic testing treatment
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
of anemia and hemolysis ... Immune-mediated Hemolysis ... : • Autoimmune ... Nonimmune-mediated Hemolysis ... #Anemias #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... Extravascular Hemolysis ... EricsMedicalLectures/ #Hemolysis ... Extravascular #Causes #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Intravascular - Hemolysis ... anemia • ... malformations #Hemolysis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... anemia • Cold ... • Compensated hemolysis ... younger pts) Differential ... intravascular hemolysis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold ... elliptocytosis, autoimmune ... hemolysis) ARUPConsult ... #Anemia #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... Defects: Sickle cell anemia ... Urobilinogen #Hemolysis
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... carcinoid, Mets), COPD ... Necrotizing PNA, Abscess ... Rheumatologic / Autoimmune ... AVM, Thoracic aortic
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Pathophysiology ... Leukocytosis, anemia ... > 10 days - Hemoptysis ... Coli - P. ... Differential Diagnosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... schistosomiasis • Pyemia ... Brucellosis Faget's Sign ... with profound hemolysis ... Fever #Patterns #Differential
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