45 results
diagnosis hepatology differential algorithm management liver pathophysiology lfts causes obstetrics pregnancy primary biliary cirrhosis comparison pbc cancer cholangitis gastroenterology hellp
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltrates maternal hepatocytes ... iMedEducation #AFLP
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP
Causes of AKI in Pregnancy - Differential Diagnosis Creatinine - Platelets - Transaminases - LDH - PT/PTT
Nephritis • AFLP
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
(Alk phos/ULN ALP ... • AST/ALT > ALP ... Cholestasis • ALP ... disease • If ALP ... • Elevation of ALP
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP)
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Diagnosis Algorithm ALP ... - Increased ALP ... Surgical consult ALP ... #Phosphatase #ALP
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