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diagnosis dermatology rash clinical differential algorithm photo management skin rheumatology nejm physicalexam pediatrics causes disease skinrash video derm signs symptoms
NAFLD Activity Score (NAS) 0–3 for steatosis 0–3 for inflammation 0–2 for ballooning hepatocytes NAS ≥5 is classified as definitive
Activity Score (NAS ... for ballooning hepatocytes ... NAS ≥5 is classified ... as definitive NASH ... Activity #Score #NAS
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
Steatohepatitis (NASH ... NASH is a potentially ... specimens: ballooned hepatocytes ... distribution of NASH ... #Epidemiology #NASH
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
develop in fatty hepatocytes ... Pathophysiology #GI #IM #NASH
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte
NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year →
NAFLD / NASH Progression ... Liver → NAFLD/NASH ... year → Cirrhotic NASH ... → HCC • NAFLD/NASH ... → Cirrhotic NASH
Hepatic Portal Venous System Drainage Anatomy 1) Most of the blood from abdominal organs goes into the
is delivered to hepatocytes
Assessment of Nonalcoholic Steatohepatitis (NASH) Severity in Patients With Nonalcoholic Fatty #Diagnosis #Pathology #NAFLD #NASH #Fibrosis #Staging
Steatohepatitis (NASH ... Pathology #NAFLD #NASH
Rash Morphology Description Algorithm #Rash #Morphology #Description #Algorithm #Skin #Dermatology #Diagnosis
Rash Morphology ... Algorithm #Rash
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