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diagnosis allergy differential management signs symptoms hematology pulmonary acid airway antibiotics classification cold criteria hypoxia immunology indications manifestations organsystems pathophysiology
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Usually occurs with urticaria ... usually occurs with urticaria ... • Hereditary ... cell-mediated in > 90% of cases
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... Female predominance Anaphylaxis ... lesions - Wheals/angioedema ... fever, fatigue, Nausea ... #rheumatology #comparison
Hypoxemia / Hypoxia - Rapid Response Management Algorithm Stridor - Upper airway pathology: • Anaphylaxis • Foreign
Hypoxemia / Hypoxia ... Response Management Algorithm ... pathology: • Anaphylaxis ... Foreign body • Angioedema ... Diagnosis #Management #Algorithm
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... Wheezing, dyspnea, hypoxia ... • Angioedema ... ischemia) • Urticaria ... • Angioedema
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
manifestations of anaphylaxis ... doom. headache Angioedema ... Mucosa 80-90%): Urticaria ... arrest GI (>40%): Nausea ... incontinence #anaphylaxis
Stridor - Differential Diagnosis Framework: High-pitched, variable respiratory sound ETIOLOGIES: Infectious: • Retropharyngeal abscess • Acute epiglottitis • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... differential #diagnosis #causes
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... : Urine Common Uses ... rapid injection; Nausea ... Hypersensitivity & anaphylaxis
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Manifestations of Anaphylaxis ... - Oral mucosa: angioedema ... lips - Skin: urticarial ... piloerection, angioedema ... Gastrointestinal - Nausea
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 Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
lgE-Mediated) HSR - Anaphylaxis ... , Angioedema, Wheezing ... Hypotension, Hives/urticaria ... #Prescription #algorithm
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Dangerous secondary causes ... : • Anaphylaxis ... • Angioedema ... infections • Chronic Urticaria ... pass = Primary Causes
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