18 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
: • Acute allergic ... exposure • Non-allergic ... urticaria • Hereditary ... • Bradykinin ... • Bradykinin-mediated
Angioedema - Diagnostic Algorithm

#Diagnosis #Allergy #Angioedema #Hereditary #Acquired #C1Inhibitor #Bradykinin #Algorithm
Angioedema - Diagnostic ... #Diagnosis #Allergy ... #Angioedema #Hereditary ... #C1Inhibitor #Bradykinin
Causes of Angioedema: Differential Diagnosis Framework
Mast-cell mediated:
 • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
IgE dependent allergic ... NSAlDs, Aspirin Bradykinin ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... Diagnosis #Causes #allergy
Pathophysiology of ACE inhibitor-induced angioedema: Angioedema is a vascular reaction associated with tissue (subcutaneous, submucosal) edema
inhibitor-induced angioedema ... : Angioedema is ... are bradykinin ... Pathophys #EM #IM #Allergy ... #Kininogen #Bradykinin
Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
Swelling from Hereditary ... Angioedema on Physical ... 19 year old Hereditary ... Angioedema (HAE ... #PhysicalExam #allergy
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
Foreign body Allergic ... /Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... exposure to a likely allergen ... exposure to known allergen ... dyspnea, hypoxia • Angioedema ... Urticaria • Angioedema
Bradykinin-mediated Angioedema
Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Bradykinin-mediated ... Angioedema Clinical ... pain Types: • Hereditary ... #mediated #Angioedema ... #allergy #immunology
There are 2 Major Types of Angioedema:
 - Mast cell / histamine mediated – usually presents
Major Types of Angioedema ... AND allergic symptoms ... hypotension) - Bradykinin ... presents WITHOUT allergic ... Classification #Types #Bradykinin
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
manifestations of anaphylaxis ... doom. headache Angioedema ... incontinence #anaphylaxis ... diagnosis #criteria #allergy