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diagnosis allergy differential hematology management table classification signs symptoms treatment types acid acquired acute airway algorithm anesthesia anesthesiology c1inhibitor champs
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... urticaria • Hereditary ... cell-mediated in > 90% of cases ... • Bradykinin ... • Bradykinin-mediated
Angioedema - Diagnostic Algorithm #Diagnosis #Allergy #Angioedema #Hereditary #Acquired #C1Inhibitor #Bradykinin #Algorithm
Angioedema - Diagnostic ... Diagnosis #Allergy #Angioedema ... #Hereditary #Acquired ... #C1Inhibitor #Bradykinin
Causes of Angioedema: Differential Diagnosis Framework Mast-cell mediated: • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... NSAlDs, Aspirin Bradykinin ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... Differential #Diagnosis #Causes
Stridor - Differential Diagnosis Framework: High-pitched, variable respiratory sound ETIOLOGIES: Infectious: • Retropharyngeal abscess • Acute epiglottitis • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... differential #diagnosis #causes
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... : Urine Common Uses ... rapid injection; Nausea ... Hypersensitivity & anaphylaxis
Bradykinin-mediated Angioedema Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Bradykinin-mediated ... Angioedema Clinical ... pain Types: • Hereditary ... female, ACEI) Bradykinin ... #mediated #Angioedema
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... deposition disease, hereditary ... angioedema A -
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
manifestations of anaphylaxis ... doom. headache Angioedema ... arrest GI (>40%): Nausea ... incontinence #anaphylaxis
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Manifestations of Anaphylaxis ... - Oral mucosa: angioedema ... piloerection, angioedema ... Gastrointestinal - Nausea ... Signs #Symptoms #Anaphylaxis
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 Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... Female predominance Anaphylaxis ... lesions - Wheals/angioedema ... fever, fatigue, Nausea ... #rheumatology #comparison
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