13 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... urticaria • Hereditary ... angioedema - Rare ... • Bradykinin ... • Bradykinin-mediated
Angioedema - Diagnostic Algorithm

#Diagnosis #Allergy #Angioedema #Hereditary #Acquired #C1Inhibitor #Bradykinin #Algorithm
Angioedema - Diagnostic ... Diagnosis #Allergy #Angioedema ... #Hereditary #Acquired ... #C1Inhibitor #Bradykinin
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... • Vocal cord
Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
Swelling from Hereditary ... Angioedema on Physical ... Examination 19 year old ... Hereditary Angioedema ... #Angioedema #clinical
Causes of Angioedema: Differential Diagnosis Framework
Mast-cell mediated:
 • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... NSAlDs, Aspirin Bradykinin ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... angioedema) •
An Algorithm for the Diagnosis of Wheezing and Stridor

Stridor: Louder, constant-pitch sound over central airways
Wheezing: Musical
Inflammatory: Anaphylaxis ... , Angioedema, Epiglottitis ... Functional: Vocal fold ... Paradoxical vocal fold ... , Anaphylaxis, Carcinoid
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Cold Urticaria Prevalence ... skin contact with cold ... Female predominance Anaphylaxis ... lesions - Wheals/angioedema ... #rheumatology #comparison
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis
Hypoxemia / Hypoxia - Rapid Response Management Algorithm

Stridor - Upper airway pathology:
 • Anaphylaxis
 • Foreign
pathology: • Anaphylaxis ... Foreign body • Angioedema ... Epiglottitis • Vocal cord ... pneumothorax, COPD
Bradykinin-mediated Angioedema
Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Bradykinin-mediated ... Angioedema Clinical ... pain Types: • Hereditary ... female, ACEI) Bradykinin ... #mediated #Angioedema