24 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Diagnosis and Treatment ... urticaria • Hereditary ... • Bradykinin ... • Bradykinin-mediated ... Classification #Types #Diagnosis
Angioedema - Diagnostic Algorithm

#Diagnosis #Allergy #Angioedema #Hereditary #Acquired #C1Inhibitor #Bradykinin #Algorithm
Angioedema - Diagnostic ... Algorithm #Diagnosis ... #Allergy #Angioedema ... #Hereditary #Acquired ... #C1Inhibitor #Bradykinin
Causes of Angioedema: Differential Diagnosis Framework
Mast-cell mediated:
 • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
: Differential Diagnosis ... NSAlDs, Aspirin Bradykinin ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... #Differential #Diagnosis
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
- Differential Diagnosis ... Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... #differential #diagnosis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... and Symptoms Anaphylaxis ... dyspnea, hypoxia • Angioedema ... Urticaria • Angioedema ... pathophysiology #immunology #diagnosis
Bradykinin-mediated Angioedema
Clinical features: Submucosal oedema (face, extremity, genitalia), Laryngeal dyspnea (25% of deaths), Recurrent attacks of
Bradykinin-mediated ... Angioedema Clinical ... pain Types: • Hereditary ... #mediated #Angioedema ... allergy #immunology #diagnosis
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis
There are 2 Major Types of Angioedema:
 - Mast cell / histamine mediated – usually presents
Major Types of Angioedema ... presents with angioedema ... hypotension) - Bradykinin ... think ACEi #Diagnosis ... #Types #Bradykinin
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
manifestations of anaphylaxis ... doom. headache Angioedema ... incontinence #anaphylaxis ... signs #symptoms #diagnosis
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
deposition disease, hereditary ... angioedema A - ... CHAMPS #Mnemonic #diagnosis