21 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
: • Acute allergic ... exposure • Non-allergic ... urticaria • Hereditary ... or avoiding the allergen ... Treatment #management #allergy
Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
Swelling from Hereditary ... Angioedema on Physical ... 19 year old Hereditary ... Angioedema (HAE ... #PhysicalExam #allergy
Stridor - Differential Diagnosis Framework:
High-pitched, variable respiratory sound

ETIOLOGIES:
Infectious:
 • Retropharyngeal abscess
 • Acute epiglottitis
 • Peritonsillar
Foreign body Allergic ... /Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... exposure to a likely allergen ... exposure to known allergen ... dyspnea, hypoxia • Angioedema ... Urticaria • Angioedema
Angioedema - Diagnostic Algorithm

#Diagnosis #Allergy #Angioedema #Hereditary #Acquired #C1Inhibitor #Bradykinin #Algorithm
Angioedema - Diagnostic ... #Diagnosis #Allergy ... #Angioedema #Hereditary
Causes of Angioedema: Differential Diagnosis Framework
Mast-cell mediated:
 • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... IgE dependent allergic ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... Diagnosis #Causes #allergy
Manifestations of Anaphylaxis by Body System

Dermatologic/mucosal

 - Eyes: periorbital swelling/erythema, injected conjunctiva, tears

 - Oral mucosa:
Manifestations of Anaphylaxis ... - Oral mucosa: angioedema ... piloerection, angioedema ... : bradycardia, shock ... play #Diagnosis #Allergy
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
manifestations of anaphylaxis ... doom. headache Angioedema ... incontinence #anaphylaxis ... diagnosis #criteria #allergy
Bedside Classification of Shock

Hypovolemic shock 

- Vomiting, diarrhea, overdiuresis 

- Hemorrhage (GI, peritoneal, RP) 

Distributive shock
Classification of Shock ... Hypovolemic shock ... - Septic shock ... Adrenal crisis - Anaphylaxis ... #Cardiogenic #Comparison
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis