21 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... lesions Abdominal pain ... Thrombocytopenia #Lupus #SLE ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Lupusreference #SLE ... #Systemic #Lupus ... autoantibodies #signs #symptoms ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... erythematosus (SLE ... ANA #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Neurologic system ... conditions #joint #pain ... #differential # ... diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Seen in: • Systemic ... • Fever is the main ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Polyarteritis Nodosa (PAN ... Arthritis (RA), Systemic ... erythematosus (SLE ... #Diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... months to years) Systemic ... comparison #table #rheumatology ... #diagnosis #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... the face (many differential ... #clues #system ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint pain ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... constitutional symptoms ... arthritis • SLE ... #Differential # ... Diagnosis #MSK #rheumatology