21 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... #Causes #differential ... diagnosis #calcium #high ... #endocrinology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... uw_IMresidency #Hypercalcemia ... #Workup #Differential ... Diagnosis #algorithm #endocrinology
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypocalciuric Hypercalcemia ... Low PTH: • High ... calcitriol induced hypercalcemia ... @aishaikh #Hypercalcemia
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Elevated PTH (High ... Hypocalciuric Hypercalcemia ... Low PTH: • Elevated ... Thiazides/Lithium #Hypercalcemia
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... PTH - Frankly high ... FeCa <1 %) - Low ... BrighamChiefs #Hypercalcemia ... #workup #differential
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Diagnostic Approach to Hyperkalemia ... transplant - SLE High ... Ketoconazole Low ... Beta-Blockers #Hyperkalemia ... Algorithm #diagnosis #differential
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Insufficiency Differential ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... insufficiency likely: • High ... Diagnosis #Algorithm #endocrinology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
abnormalities - Hypercalcemia ... Hypomagnesemia #Differential ... #Diagnosis #Low ... Magnesium #Table #Classification ... #Causes #Workup
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Reduced Excretion - Differential ... • NSAlDs #Hyperkalemia ... IntercellularShift #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Drug-induced • High ... Sarcoidosis • Hypercalcemia ... Diagnosis #Algorithm #endocrinology ... #causes