14 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... #Causes #differential ... #high #endocrinology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... requirements - Lack of hypercalcemia ... range - Lack of hypercalcemia ... #Comparison #Pharmacology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... uw_IMresidency #Hypercalcemia ... Diagnosis #algorithm #endocrinology ... #calcium
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Bony Mets - Calcium ... Thiazides/Lithium #Hypercalcemia ... #endocrinology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
since they are not able ... safety reasons) and calcium ... The use of calcium-based ... restricted due to hypercalcemia ... #Dose #Dosing #Pharmacology
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
hypercalciuria, Hypercalcemia ... phosphate - Inner ... hypercalciuria, Hypercalcemia ... Renal #stones #differential ... #diagnosis #causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... magnesium, and calcium ... Potassium #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... Lithium use • Calcium-sensing ... hypocalciuric hypercalcemia ... Milk-alkali syndrome #Hypercalcemia ... #Causes #endocrinology
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... BrighamChiefs #Hypercalcemia ... #workup #differential ... #diagnosis #endocrinology ... #calcium #elevated
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... • LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... potassium and calcium ... Dialysis for severe hyperkalemia