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diagnosis management causes nephrology oncology algorithm classification product reactions acute aki calcium diuresis diuretics emergencies encephalopathy excretion hodgkins hypertension indications
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... hypocalciuria, Thiazides Hypercalcemia ... intoxication #Hypercalcemia
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... • Milk-alkali syndrome ... #Hypercalcemia ... #Causes #endocrinology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperphosphatemia • Hyperkalemia ... renal failure • Hypocalcemia ... Hypercalcemia ... #diagnosis #cancer
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Cancer Related ... • Hypercalcemia ... change disease • Hematologic ... malignancies Treatment ... #Oncology #Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... UA positive for blood ... Dialysis for severe hyperkalemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup and Differential ... disorders including hypokalemia ... Vasculitis • Endocrinologic ... Hyperthyroidism, Hypercalcemia ... Workup #causes #Differential
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... organ damage • Treatment ... Spontaneous if high ... hydration - Hyperkalemia ... diagnosis #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Autoimmune disease, Cancer ... transfusion, Hypercalcemia ... Reversible course Differential ... elevated white blood ... epilepticus Treatment
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... Prevention of blood ... Tolvaptan) • Treatment
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