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diagnosis causes nephrology management potassium algorithm oncology renal rhabdomyolysis table tumorlysis types uricacid workup acidosis acute aki aniongap calcium calculi
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... hypocalciuria, Thiazides Hypercalcemia ... intoxication #Hypercalcemia
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... urinary excretion ... urine pH) • Hypocalcemia ... • Hyperkalemia
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
(TLS) and Treatment ... other symptomatic hypocalcemia ... Treatment of TLS ... hydroxide • Hyperkalemia ... • Hypocalcemia
Multiple Endocrine Neoplasias (MEN syndromes) MEN I • Hyperparathyroidism • Hypercalcemia • Possible ZE syndrome • Various
Hyperparathyroidism • Hypercalcemia ... Hyperparathyroidism • Hypercalcemia ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology ... #Classification
Workup of Hypercalcemia - Differential Diagnosis Algorithm High or Normal PTH: • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypocalciuric Hypercalcemia ... calcitriol induced hypercalcemia ... Infantile idiopathic hypercalcemia ... @aishaikh #Hypercalcemia
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... Guillain-Barré syndrome ... Hyperreflexia: • Hypocalcemia ... Testing #Causes #differential ... diagnosis #table #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Dialysis for severe hyperkalemia ... #nephrology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Primary - Under-excretion ... Drug-induced • High ... Sarcoidosis • Hypercalcemia ... Diagnosis #Algorithm #endocrinology
Classification of Diabetes Insipidus Central or neurogenic diabetes insipidus: - Congenital - Structural malformations affecting the hypothalamus
Classification of ... causes (e.g., hypokalemia ... , hypercalcemia) ... Treatment is aimed ... #Diagnosis #Differential
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... cantaloupe #hyperkalemia
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