11 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... 8.0 mg/dL • Potassium ... other symptomatic hypocalcemia ... hydroxide • Hyperkalemia ... • Hypocalcemia
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... transfusion • Tumor lysis ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm ... #differential
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... Diagnosis Algorithm ... R/O Pseudo-hyperkalemia ... plasma [K+] #Hyperkalemia ... Diagnosis #Algorithm
Constipation - Differential Diagnosis Algorithm
Diet/Lifestyle
 • Fibre
 • Calories
 • Fluid
 • Exercise
 • Psychosocial
Medications
 •
Diagnosis Algorithm ... , Potassium) • ... Hypothyroidism • Hypokalemia ... • Hypercalcemia ... #Diagnosis #Algorithm
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... calcium • IV ... , asystole #hyperkalemia ... #diagnosis #management ... #algorithm #treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia ... #Treatment #potassium
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
Bradycardia Diagnostic ... and Management Algorithm ... THREATENING CAUSES & TREATMENT ... Electrolytes (hyperkalemia ... #Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... hydration - Hyperkalemia ... treatment (no calcium ... Syndrome #TLS #diagnosis ... #management #hematology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... Pump - Digoxin works ... - Hyperkalemia ( ... , in states of hypokalemia ... #cardiology