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Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
myopathies - Excess exertion ... declines > ALT) • AKI ... + myoglobin AKI ... per day until stable ... #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... Cancer Related • Hypercalcemia ... gammopathy of renal ... malignancies Treatment ... Classification #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
deficiency, Salt-losing ... antidiuretic hormone secretion ... Hypervolemia, ... failure Hypervolemia ... Algorithm #Causes #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... myopathies, Excess exertion ... Dermatomyositis) AKI ... per day until stable ... Dialysis for severe hyperkalemia
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... - Tumor lysis syndrome ... Excretion: • ... deficiency • Renal ... potassium #high #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Losses (AKI, Post-AKI ... : Hypovolemia, Hypervolemia ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... - Tumor lysis syndrome ... Excretion: • ... deficiency • Renal ... potassium #high #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute pulmonary ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology ... #Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+ Excretion: ... , RTA Type IV, AI ... excretion ... Elimination (see Table ... #potassium #nephrology
Pharmacologic Options for Hypercalcemia Associated with Cancer
Rehydration with NS followed by loop diuretics
 • IV normal
Pharmacologic Options ... for Hypercalcemia ... excretion of Ca2 ... management #drugs #treatment ... table