12 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Low pill burden. ... Low pill burden ... #Table #Comparison ... #Pharmacology # ... Nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
calcium for K; also binds ... nonspecifically binds ... #medications #pharmacology ... #table #comparison ... #binders
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... increased risk of low ... #Table #Comparison ... #Pharmacology # ... Nephrology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... since they are not able ... restricted due to hypercalcemia ... Only* #CKD #Nephrology ... #Dose #Dosing #Pharmacology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Thyrotoxicosis Medications ... vomiting) • Low ... #nephrology #low
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... acidosis) • Low ... Treatment #potassium #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table ... #sodium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Hyponatremia • Hypercalcemia ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table