11 results
diagnosis management lupus rheumatology differential neurology erythematosus nephritis systemic biopsy cerebritis classification clinical cns comparison cord disorders druginduced granuloma indications
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... constitutional symptoms • Treatment ... 80% - Low complement ... life-threatening • Treatment ... Evolution: Chronic disease
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Positive in 60-80% of cases ... 80% - Low complement ... life-threatening • Treatment ... Evolution: Chronic disease
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... (MPA) • SLE ... Minimal change disease ... #Proteinuria #Nephrology ... #Causes
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Treatment of Membranous ... treat non-renal SLE ... for worsening disease ... #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE ... #CNS #neurology
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
approach to kidney disease ... , WBC casts) especially ... Non-LN Kidney Disease ... Nephritis #diagnosis #algorithm ... #sle #nephrology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Evaluate for NMO, SLE ... • Infectious causes ... Disorders: - SLE ... Transverse Myelitis Treatment ... diagnosis #management #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... Xerostomia • Dental caries ... Adenocarcinoma Treatment
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Non-compressive Spinal Cord Causes ... Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... disorders #diagnosis #neurology ... differential #algorithm
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