13 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Erythematosus (total 50, renal ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... #differential #hematology
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis Classification ... Algorithm #Lupus ... #Algorithm #diagnosis ... differential #types #rheumatology ... #nephrology #renal
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... pericarditis • Hematologic ... hemolysis • Renal ... anticoagulant • Complement ... #EULARACR #Classification
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... Renal Disease, Liver ... #Anemia #MCV #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Purpura - Diagnostic Algorithm ... Pathophysiology: ... affected (commonly renal ... #Diagnosis #Dermatology ... Purpura #Palpable #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... Urticaria and hypocomplementemia ... against MPO • Complement ... • Urinalysis (Renal ... #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis ... #differential #algorithm
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
vasodilation → ↓ renal ... perfusion + ↑ renal ... Pathophysiology: ... Classification: ... Hepatorenal #Syndrome #Hepatology