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differential causes dermatology rheumatology hematology classification management pulmonary sle nephrology disorders alopecia erythematosus hairloss rash renal skin workup acute comparison
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Algorithm Reactive ... • Systemic Lupus ... #Algorithm #Causes
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... anticoagulant - Low complement ... hemolytic anemia #Diagnosis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... Speckled: Systemic lupus ... • Nucleolar: Diffuse ... #rheumatology #diagnosis
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... • Discoid lupus ... #Differential #Diagnosis ... #Algorithm #causes
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Lupus #Nephritis ... Classification #Algorithm ... #diagnosis #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... Class II or V lupus ... anticoagulant • Complement ... Erythematosus #diagnosis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
- Differential Diagnosis ... Framework Diffuse ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... #Differential #Diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... , oral ulcers, Lupus ... 80% - Low complement ... Erythematosus #Diagnosis
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