17 results
diagnosis differential rheumatology sle management erythematosus nephrology systemic alopecia comparison dermatology hairloss hematology table vasculitis acute aki allergy champs criteria
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... IV - Diffuse Proliferative ... #Nephritis #SLE ... #Classification ... #Classes #differential
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... IV - Diffuse LN ... glomeruli) Diffuse
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... II or V lupus nephritis ... , Class Ill or IV ... lupus nephritis ... anticoagulant • Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... differential #diagnosis #algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... pneumonitis • Diffuse ... enteropathy, and diffuse ... RNP antibodies, Complement
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... IgA, post-strep, lupus ... and >3.5g/day (nephrotic ... #Causes
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Systemic Lupus ... Hodgkin's Lymphoma #Diffuse ... #Causes #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... nephritis, NPSLE ... Positive in 60-80% of cases ... 80% - Low complement
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Differential Diagnosis Algorithm ... IgA, post-strep, lupus ... Acute Interstitial Nephritis ... #Causes
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