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diagnosis rheumatology differential erythematosus management systemic ana causes antibodies classification dermatology vasculitis alopecia criteria druginduced hairloss laboratory mnemonic patterns summary
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... • Nucleolar: Diffuse ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... #differential #hematology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Discoid Rash A Antinuclear ... Pleuritis) H Hematologic ... #IMDAMNSHARP #sle ... #systemic #lupus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Farr assay) and lupus ... Lupusreference #Antinuclear ... erythematosus #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus (SLE ... • Nucleolar: Diffuse ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... • Specific for SLE ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... 80% - Low complement ... #lupus #Systemic ... Management #Summary #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... pericarditis • Hematologic ... anticoagulant • Complement ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement ... #table #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic Lupus ... anticoagulant - Low complement ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
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