26 results
diagnosis differential causes hematology workup disease management rheumatology deficiency glomerular glomerulonephritis hemolytic nephrology nephrotic pancytopenia pathophysiology treatment abscess agglutinin allergy
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... When to Consider Vasculitis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... cardiac valve, vasculitis ... ARUPLabs #Hemolytic #Anemia ... workup #hematology #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... • Symptoms of anemia ... • hemolytic anemia ... Positive Coombs testing ... temperatures by fixing complement
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... immune-complex hemolytic anemia ... Differential #Diagnosis #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... HUS • DIC • Vasculitis ... Differential #Diagnosis #Algorithm
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Differential Diagnosis Algorithm ... hypertension • Vasculitis ... • Anxiety • Anemia ... Differential #Diagnosis #Algorithm
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Differential Diagnosis Algorithm ... Hyperemia Spasm • Vasculitis ... • Sickle Cell Anemia ... Air Embolism • Vasculitis ... Differential #Diagnosis #Algorithm
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Differential Diagnosis Algorithm ... malformation, Aneurysm, Vasculitis ... Cerebral Hypoxia, Uremia ... Differential #Diagnosis #Algorithm
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