17 results
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... agent • Does not cause ... hypoglycemia ... #DM2 #diabetes ... #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... : Weight gain, Hypoglycemia ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology Summary ... not definitively cause ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology Summary ... not definitively cause ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management Summary ... old, ~10,000 new cases ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... Positive in 60-80% of cases ... life-threatening • Treatment ... Diagnosis #Management #Summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... Treatment: • ... Etoposide/VP16 (100 mg/m2 ... diagnosis #management #treatment ... #summary #rheumatology
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
hypercalcemia, Hyperglycemia ... ↑ AST/ALT • Treatment ... tenderness Treatment ... hyperthyroidism #causes ... #differential #endocrinology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management Summary ... • Most common cause ... pneumonia • DM ... hemorrhage • Treatment ... #differential #causes
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
and Management Summary ... Pegvisomant) ± D2 ... or refractory cases ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology