11 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... , Hematology 2012 ... #Diagnosis #Differential ... #Algorithm #Thrombocytopenia
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... - Differential ... artery aneurysm: Causes ... arterial clot, ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... #Differential # ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... Diagnosis Algorithm ... following EtOH induced thrombocytopenia ... #Causes #Hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Diagnosis Algorithm ... Retained blood clots ... • Thrombotic thrombocytopenic ... purpura (TTP)
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic ... purpura (TTP), ... #differential # ... diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• TMA’s (HUS/TTP ... significant fibrin clot ... Schistocytes - MAHA: TTP ... Treat primary cause ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential ... Hyperviscosity, TTP ... Heparin-induced thrombocytopenia ... coagulation and other causes ... pathophysiology #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... hypersplenism and related thrombocytopenia ... (hepatic vein clot ... • Portal vein thrombosis ... #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Evaluation for Thrombotic ... Thrombocytopenic ... WBC count and differential ... Diagnosis #Workup #Hematology