26 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... Complications: • Gonadal hypoplasia ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
Vaccine-induced ... Symptoms of VITT ... and neurological symptoms ... that while the diagram ... thrombocytopenia #COVID #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Glucocorticoid-Induced ... Fat emboli -> Reduced ... #Osteoporosis #pathophysiology ... #signs #symptoms
Clinical features of shock from dehydration in an infant

Decreased level of consciousness 
Sunken fontanelle 
Dry mucous
peripheral pulses Reduced ... Sudden weight loss Reduced ... PhysicalExam #Signs #Symptoms ... #Dehydration #Peds
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Hypocellular/Hypoplastic ... Level ↑ • Marrow hypoplasia ... cells is much reduced ... • Improve the symptoms
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
• Tolerance (reduced ... recreational activities reduced ... • Withdrawal symptoms ... AlcoholUseDisorder #EtOH #Pathophysiology ... Diagnosis #Signs #Symptoms
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
movement with reduced ... Osteoarthritis #OA #pathophysiology ... diagnosis #signs #symptoms
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... improvement in symptoms ... analyses showed reduced
Magnesium Deficiency and Alcoholism

Risks associated with Mg deficiency in alcoholism:
 • Affects protein synthesis. energy production,
development of alcohol-induced ... • Depressive symptoms ... Alcoholism #alcohol #pathophysiology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
bacterial metabolites induce ... hemorrhagic rash; symptoms ... non-specific viral symptoms ... #Immunization #peds ... #pediatrics #pathophysiology