21 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Insufficiency, Liver ... • Obstructive: Pulmonary ... Pneumothorax, Cardiac ... Abdominal compartment syndrome ... #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
nose deformity • Cardiac ... (UPC) ratio • Cardiac ... o infection • Echocardiogram ... differential #diagnosis #management ... #treatment
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... left heart 3-6 cardiac ... ) on room air Treatment ... supplemental oxygen if ... #treatment #hepatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... , DIC, TMA • Cardiac ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Bicytopenia Treatment ... If no response HLH ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... irrigation • Management ... Torsemide) • Acute pulmonary ... • Bleeding • Cardiac ... Tolvaptan) • Treatment
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
Transthoracic echocardiogram ... pressure < 15mmHg TREATMENT ... hemodynamics Liver ... Hypertension #diagnosis #management ... #hepatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... → no immediate treatment ... after CRS) - Treatment ... renal failure, pulmonary ... pleural effusions - Treatment