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differential algorithm hematuria nephrology hypertension secondary acute htn injury kidney urine cardiology failure indications macroscopic management membranoproliferative mpgn nonglomerular postrenal
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... for renal biopsy ... and referral to Urology ... by UW IM Residency ... #urology #blood
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Workup Algorithm ... and signs • Glomerulonephritis ... cryoglobulins, hepatitis serology ... , HIV serology, ... #nephrology #causes
Causes of Hematuria - Glomerular vs Non-glomerular == Glomerular == - Glomerulonephritis - Thin basement membrane disease ==
Causes of Hematuria ... == - Glomerulonephritis ... Pyelonephritis - Renal ... #Algorithm #Diagnosis ... #Differential #Urology
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
and Differential Diagnosis ... RBC’s, RBC/WBC casts ... suggest intrinsic renal ... #EM #IM #Urology ... Differential #Algorithm #Ddxof
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... urine • 1ml blood ... #causes #urology ... #nephrology #renal ... #urine #blood
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... immune deposits on EM ... #MPGN #nephrology ... #diagnosis #renal
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... Kidney Injury ( AKI ... • Sepsis • Blood ... Glomerulonephritis ... /phimosis #Diagnosis
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... - Differential Diagnosis ... Renal: - Glomerular ... syndrome, Other glomerulonephritis ... #Causes #urology
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm Primary (Essential) (95%) - Onset between age
- Differential Diagnosis ... Repeatedly normal blood ... taken at home, work ... disease - CKD, AKI ... , Glomerulonephritis
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
visits, Ambulatory blood ... multi-drug resistance) Renal ... Parenchymal Diseases • Glomerulonephritis ... Nephritic syndrome • AKI ... HTN #Secondary #Nephrology
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