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differential management hemolysis intravascular oncology algorithm blood clinical extravascular hemolytic photo product reactions rheumatology skin syndrome activation aplastic atopic atopy
Causes of Hypocalcemia #Diagnosis #EM #IM #Endo #Hypocalcemia #Differential #Algorithm #PTH #Drugs #Ddxof
Causes of Hypocalcemia ... #Diagnosis #EM ... #IM #Endo #Hypocalcemia ... Differential #Algorithm #PTH ... #Drugs #Ddxof
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... immune-complex hemolytic anemia ... • MAHA (TTP, DIC ... #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
formerly known as ... transplant • DIC ... macroangiopathic hemolytic anemia ... Catastrophic APLS BCM IM ... #hematology #hemolysis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... deficiencies - PNH ... #hematology #rheumatology ... #nonpalpable #dermatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... MAHA: TTP, HUS, DIC ... , HELLP, AS, prosthetic ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... MAHA: TTP, HUS, DIC ... Grafts, Valves, AS ... Defects: Sickle cell anemia ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Fibrinolysis → End ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... intravascular coagulation (DIC ... hemoglobinuria (PNH ... #hematology #anemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... result in severe anemia ... Haptoglobin - Low as ... immune hemolytic anemia ... #Workup #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... : - Neuro: AMS ... + lab signs of end ... Syndrome #TLS #diagnosis ... #management #hematology
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